Uremic Solutes Database
Solute Details for N(6)-Carboxymethyllysine (CML)
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Base data
Name N(6)-Carboxymethyllysine (CML)
Molecular weight 204
Group AGE
Class Protein-bound [4]
Added 16.09.2009
Reference Pubmed: 12675874
Submitted by Vanholder
Reviewed by Abou Deif

Normal concentrations (CN)
DateMean (+/-SD) (low Range - high Range)nReferenceSubmitted byReviewed byNotes
24.08.20001.10 (+/-0.30) mg/L24Mechanisms for the formation of glyco...VanholderAbou Deif
Grand mean1.10 (+/-0.30) mg/L24
ANOVA
Dispersion

Uremic concentrations (CU)
DateMean (+/-SD) (low Range - high Range)nReferenceSubmitted byReviewed byNotes
24.08.20004.30 (+/-1.30) mg/L44Mechanisms for the formation of glyco...VanholderAbou Deif
02.07.20031.84 (+/-0.08) mg/L74Relationship between plasma level of ...Abou DeifArgiles
11.07.200618.50 (+/-5.00) mg/L10Oral adsorbent AST-120 decreases seru...Abou DeifArgiles
Grand mean3.99 (+/-1.59) (1.84-18.50) mg/L128
ANOVAF(2,125) = 443.25, p=0.00: Significant differences between group means.
DispersionL:1.84, M:3.99, H:18.50 : C - (Wide scatter: High uncertainty.)

Relative increase (CU/CN) 3.62 times higher than the average normal concentration.

Pathological associations
No clinical associations available.

Notes
4This protein-bound solute has a molecular weight conforming to middle molecules.