Uremic Solutes Database HOME   SOLUTE LIST   SOLUTE DETAILS   STATISTICS   LOGIN   REGISTER Solute Details for Tumor Necrosis Factor Alpha (TNF) Switch to solute: 1-Methyladenosine 1-Methylguanosine 1-Methylinosine 2-Heptenal 2-Hexenal 2-Nonenal 2-Octenal 3-Carboxy-4-Methyl-5-Propyl-2-Furanpropanoic Acid (CMPF) 3-Deoxyglucosone 4-Decenal 4-HO-Decenal 4-HO-Hexenal 4-HO-Nonenal 4-HO-Octenal 4-Pyridone-3-carboxamide-1-β-D-ribonucleoside 8-Hydroxy-2’-deoxyguanosine Adiponectin Adrenomedullin Angiogenin Arab(in)itol Argininic Acid Asymetric Dimethylarginine (ADMA) Atrial Natriuretic Peptide (ANP) Basic fibroblast growth factor (BFGF) Calcitonin gene-related peptide (CGRP) Cholecystokinin Clara cell protein (CC16) Complement Factor D Creatine Creatinine Cystatin C Cytidine Decanal Degranulation Inhibiting Protein I Delta-sleep Inducing Peptide Dihydroxyphenylalanine (PB-DOPA) Dimethylamine Dimethylglycine Endothelin Erythritol Ethylamine Fructoselysine Glyoxal Guanidine Guanidinosuccinic acid Guanylin Heptanal Hexanal Hippuric acid (total) Homocysteine Hyaluronic acid (Hyaluronan) Hypoxanthine Indican Indole-3-acetic acid (free) Indole-3-acetic acid (total) Indoxyl sulfate (free) Indoxyl sulfate (total) Indoxyl-β-D-glucoronide Inosine Insulin-like growth factor 1 (IGF-1) Interleukin-10 Interleukin-18 Interleukin-1β Interleukin-6 Kinurenine Kynurenic Acid Leptin Malondialdehyde (MDA) Mannitol Melatonin Methionine-Enkephalin Methylglyoxal Methylguanidine Monomethylamine Motiline Myoinositol N(6)-Carboxymethyllysine (CML) N-methyl-2-pyridone-5-carboxamide N-methyl-4-pyridone-3-carboxamide N2,N2-Dimethylguanosine N4-Acetylcytidine N6-Methyladenosine N6-Threonylcarbamoyladenosine Neopterin Neuropeptide Y Nicotinamide Nonanal Orotic Acid Orotidine Osteocalcin Oxalate p-Cresylsulfate (free) p-Cresylsulfate (total) Parathyroid hormone Pentosidine Phenol Phenylacetic acid Phenylacetylglutamine Pseudouridine Putrescine Quinolinic Acid Resistin Retinol Binding Protein (RBP) S-Adenosylhomocysteine Sorbitol Substance P Symetric Dimethylarginine (SDMA) Taurocyamine Threitol Trimethylamine Trimethylamine-N-oxide Tumor Necrosis Factor Alpha (TNF) Urea Uric Acid Uridine Uroguanylin Vascular endothelial growth factor (VEGF) Vasoactive intestinal peptide (VIP) Vasopressin (ADH) Xanthine Xanthosine α-keto-δ-Guanidinovaleric Acid α-N-Acetylarginine α1-Acid glycoprotein β-2-Microglobulin β-Endorphin β-Guanidinopropionic Acid β-Lipotropin γ-guanidinobutyric Acid λ-Ig Light Chain Base data Name Tumor Necrosis Factor Alpha (TNF) Molecular weight 26000 Group Cytokine Class Middle molecule Added 16.09.2009 Reference Pubmed: 12675874 Submitted by Vanholder Reviewed by Abou Deif Normal concentrations (CN) Date Mean (+/-SD) (low Range - high Range) n Reference Submitted by Reviewed by Notes 16.09.1998 13.30 (+/-3.00) ng/L 28 Immunologic function and survival in ... Vanholder Abou Deif Grand mean 13.30 (+/-3.00) ng/L 28 ANOVA Dispersion Uremic concentrations (CU) Date Mean (+/-SD) (low Range - high Range) n Reference Submitted by Reviewed by Notes 27.06.1994 1419.00 (+/-434.00) (160.00-5600.00) ng/L 29 Plasma levels of IL-1 beta, TNF alpha... Abou Deif Argiles 09.09.1998 52.00 (+/-24.50) ng/L 13 Anorexigen (TNF-alpha, cholecystokini... Abou Deif Argiles 16.09.1998 114.00 (+/-147.00) ng/L 230 Immunologic function and survival in ... Vanholder Abou Deif 09.03.2000 58.70 (+/-5.00) ng/L 10 Increased plasma adrenomedullin level... Abou Deif Argiles 04.08.2003 4.90 (+/-4.90) ng/L 43 An association between aortic pulse w... Abou Deif Argiles 08.04.2008 57.80 (+/-10.80) ng/L 12 Hemodialysis acutely improves hepatic... Abou Deif Argiles Grand mean 206.35 (+/-176.03) (4.90-5600.00) ng/L 337 ANOVA F(5,331) = 303.22, p=0.00: Significant differences between group means. Dispersion L:4.90, M:206.35, H:5600.00 : D - (Wide scatter, even compared to median: Use with caution) Relative increase (CU/CN) 15.51 times higher than the average normal concentration. Pathological associations No clinical associations available. Notes No notes.