Solute Details for Creatinine - Uremic Solutes Database

Uremic Solutes Database

Solute Details for Creatinine

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Base data

Name

Creatinine

Molecular weight

113

Group

Guanidine

Class

Water-soluble

Added

16.09.2009

Reference

Submitted by

Vanholder

Reviewed by

Abou Deif

Normal concentrations (CN)

Date	Mean (+/-SD) (low Range - high Range)	n	Reference	Submitted by	Reviewed by	Notes
23.04.1973	(?-12.00) mg/L	23	Volatile phenols in serum of uraemic ...	Vanholder	Abou Deif	[10] [16]
08.06.2006	8.86 (+/-1.27) mg/L	16	Plasma guanidino compounds are altere...	Abou Deif	Argiles	[2] [15]
29.06.2015	9.70 (+/-0.16) mg/L	835	Calcium supplementation increases blo...	Abou Deif	Argiles
Grand mean	9.68 (+/-0.24) (8.86-12.00) mg/L	851
ANOVA	F(1,849) = 381.42, p=0.00: Significant differences between group means.
Dispersion	L:8.86, M:9.68, H:12.00 : A - (Minimal scatter: High consistency.)

Uremic concentrations (CU)

Date	Mean (+/-SD) (low Range - high Range)	n	Reference	Submitted by	Reviewed by	Notes
23.04.1973	136.00 (+/-46.00) (?-240.00) mg/L	19746	Volatile phenols in serum of uraemic ...	Vanholder	Abou Deif
Grand mean	136.00 (+/-46.00) (?-240.00) mg/L	19746
ANOVA
Dispersion

Relative increase (CU/CN)

14.04 times higher than the average normal concentration.

Pathological associations

Date	Category	Reference	Comment
12.04.2001	Neurologic and CNS	Endogenous guanidino compounds as ure...	May play an important role in the etiology of uremic encephalopathy.

Notes

2	Units reported as mol/l transformed to g/l as C(g/l) = [C(mol/l) * molecular weight]
10	Only maximum range available, or detection limit used as maximum range.
15	Standard error converted to standard deviation as SD = SEM * sqrt(n)
16	Excluded from analysis of variance for missing arithmetic mean, standard deviation or sample count.