Uremic Solutes Database |
Solute Details for Myoinositol |
Switch to solute: |
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Base data |
Name |
Myoinositol |
Molecular weight |
180 |
Group |
Polyol |
Class |
Water-soluble |
Added |
16.09.2009 |
Reference |
Pubmed: 12675874 |
Submitted by |
Vanholder |
Reviewed by |
Abou Deif |
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Normal concentrations (CN) |
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Uremic concentrations (CU) |
Date | Mean (+/-SD) (low Range - high Range) | n | Reference | Submitted by | Reviewed by | Notes | 07.01.1984 | 94.00 (+/-69.00) mg/L | 12 | Gas chromatographic--mass spectrometr... | Vanholder | Abou Deif | | 24.03.1994 | 43.92 (+/-9.54) mg/L | 20 | Quantification of serum 1,5-anhydrogl... | Abou Deif | Argiles | [2] | Grand mean | 62.70 (+/-42.92) (43.92-94.00) mg/L | 32 | | | ANOVA | F(1,30) = 6.73, p=0.01: Significant differences between group means. | | | Dispersion | L:43.92, M:62.70, H:94.00 : A - (Minimal scatter: High consistency.) |
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Relative increase (CU/CN) |
6.27 times higher than the average normal concentration. |
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Pathological associations |
Date | Category | Reference | Comment | 27.11.1989 | Neurologic and CNS | Myoinositol inhibits proliferation of... | Uraemic polyneuropathy seemed to be caused by a defect in maintaining normal myelin due to accumulation of myoinositol. |
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Notes |
2 | Units reported as mol/l transformed to g/l as C(g/l) = [C(mol/l) * molecular weight] | 10 | Only maximum range available, or detection limit used as maximum range. | 16 | Excluded from analysis of variance for missing arithmetic mean, standard deviation or sample count. |
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