Uremic Solutes Database
Solute Details for Pseudouridine
Switch to solute:

Base data
Name Pseudouridine
Molecular weight 244
Group Ribonucleoside
Class Water-soluble
Added 16.09.2009
Reference Pubmed: 12675874
Submitted by Vanholder
Reviewed by Abou Deif

Normal concentrations (CN)
DateMean (+/-SD) (low Range - high Range)nReferenceSubmitted byReviewed byNotes
11.08.19830.61 (+/-0.07) mg/L30Determination of pseudouridine and ot...Abou DeifArgiles[2]
24.10.19910.50 (+/-5.80) mg/L30Disturbances of cerebral purine and p...VanholderAbou Deif
Grand mean0.55 (+/-4.10) (0.50-0.61) mg/L60
ANOVAF(1,58) = 37.04, p=0.00: Significant differences between group means.
DispersionL:0.50, M:0.55, H:0.61 : A - (Minimal scatter: High consistency.)

Uremic concentrations (CU)
DateMean (+/-SD) (low Range - high Range)nReferenceSubmitted byReviewed byNotes
24.10.199113.10 (+/-21.40) (?-86.60) mg/L7Disturbances of cerebral purine and p...VanholderAbou Deif
10.09.19929.27 (+/-1.95) mg/L11Assessment of urea and other uremic m...Abou DeifArgiles
20.10.19928.60 (+/-2.70) mg/L12Pseudouridine excretion in healthy su...Abou DeifArgiles
30.07.199313.70 (+/-2.30) mg/L23Efficiency of hemodialysis of pyrimid...Abou DeifArgiles
Grand mean11.55 (+/-8.08) (8.60-86.60) mg/L53
ANOVAF(3,49) = 1.26, p=0.30: No significant differences between group means.
DispersionL:8.60, M:11.55, H:86.60 : D - (Wide scatter, even compared to median: Use with caution)

Relative increase (CU/CN) 20.80 times higher than the average normal concentration.

Pathological associations
DateCategoryReferenceComment
09.11.2000Endocrinology[Clinical significance and pathogenic...Pseudouridine inhibits glucose utilization at concentrations found in sera of uremic subjects.

Notes
2Units reported as mol/l transformed to g/l as C(g/l) = [C(mol/l) * molecular weight]