Uremic Solutes Database |
Solute Details for Xanthine |
Switch to solute: |
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Base data |
Name |
Xanthine |
Molecular weight |
152 |
Group |
Purine |
Class |
Water-soluble |
Added |
16.09.2009 |
Reference |
Pubmed: 12675874 |
Submitted by |
Vanholder |
Reviewed by |
Abou Deif |
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Normal concentrations (CN) |
Date | Mean (+/-SD) (low Range - high Range) | n | Reference | Submitted by | Reviewed by | Notes | 10.09.1992 | 0.50 (+/-1.40) mg/L | 180 | Assessment of urea and other uremic m... | Vanholder | Abou Deif | | Grand mean | 0.50 (+/-1.40) mg/L | 180 | | | ANOVA | | | | Dispersion | |
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Uremic concentrations (CU) |
Date | Mean (+/-SD) (low Range - high Range) | n | Reference | Submitted by | Reviewed by | Notes | 10.09.1992 | 1.50 (+/-0.80) mg/L | 65 | Assessment of urea and other uremic m... | Vanholder | Abou Deif | | 17.11.1994 | 0.45 (+/-0.18) mg/L | 18 | Role of adenosine in dialysis-induced... | Abou Deif | Argiles | | Grand mean | 1.27 (+/-0.71) (0.45-1.50) mg/L | 83 | | | ANOVA | F(1,81) = 6.67, p=0.01: Significant differences between group means. | | | Dispersion | L:0.45, M:1.27, H:1.50 : B - (Medium scatter: Considerable degree of uncertainty.) |
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Relative increase (CU/CN) |
2.54 times higher than the average normal concentration. |
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Pathological associations |
Date | Category | Reference | Comment | 04.02.1996 | Cardiovascular | A comparative study of the concentrat... | An increase of serum xanthine concentration in patients with myocardial infarction indicates a possible role in the development of tissue damage in the postischaemic phase. |
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Notes |
No notes. |
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