Uremic Solutes Database HOME   SOLUTE LIST   SOLUTE DETAILS   STATISTICS   LOGIN   REGISTER Solute Details for S-Adenosylhomocysteine Switch to solute: 1-Methyladenosine 1-Methylguanosine 1-Methylinosine 2-Heptenal 2-Hexenal 2-Nonenal 2-Octenal 3-Carboxy-4-Methyl-5-Propyl-2-Furanpropanoic Acid (CMPF) 3-Deoxyglucosone 4-Decenal 4-HO-Decenal 4-HO-Hexenal 4-HO-Nonenal 4-HO-Octenal 4-Pyridone-3-carboxamide-1-β-D-ribonucleoside 8-Hydroxy-2’-deoxyguanosine Adiponectin Adrenomedullin Angiogenin Arab(in)itol Argininic Acid Asymetric Dimethylarginine (ADMA) Atrial Natriuretic Peptide (ANP) Basic fibroblast growth factor (BFGF) Calcitonin gene-related peptide (CGRP) Cholecystokinin Clara cell protein (CC16) Complement Factor D Creatine Creatinine Cystatin C Cytidine Decanal Degranulation Inhibiting Protein I Delta-sleep Inducing Peptide Dihydroxyphenylalanine (PB-DOPA) Dimethylamine Dimethylglycine Endothelin Erythritol Ethylamine Fructoselysine Glyoxal Guanidine Guanidinosuccinic acid Guanylin Heptanal Hexanal Hippuric acid (total) Homocysteine Hyaluronic acid (Hyaluronan) Hypoxanthine Indican Indole-3-acetic acid (free) Indole-3-acetic acid (total) Indoxyl sulfate (free) Indoxyl sulfate (total) Indoxyl-β-D-glucoronide Inosine Insulin-like growth factor 1 (IGF-1) Interleukin-10 Interleukin-18 Interleukin-1β Interleukin-6 Kinurenine Kynurenic Acid Leptin Malondialdehyde (MDA) Mannitol Melatonin Methionine-Enkephalin Methylglyoxal Methylguanidine Monomethylamine Motiline Myoinositol N(6)-Carboxymethyllysine (CML) N-methyl-2-pyridone-5-carboxamide N-methyl-4-pyridone-3-carboxamide N2,N2-Dimethylguanosine N4-Acetylcytidine N6-Methyladenosine N6-Threonylcarbamoyladenosine Neopterin Neuropeptide Y Nicotinamide Nonanal Orotic Acid Orotidine Osteocalcin Oxalate p-Cresylsulfate (free) p-Cresylsulfate (total) Parathyroid hormone Pentosidine Phenol Phenylacetic acid Phenylacetylglutamine Pseudouridine Putrescine Quinolinic Acid Resistin Retinol Binding Protein (RBP) S-Adenosylhomocysteine Sorbitol Substance P Symetric Dimethylarginine (SDMA) Taurocyamine Threitol Trimethylamine Trimethylamine-N-oxide Tumor Necrosis Factor Alpha (TNF) Urea Uric Acid Uridine Uroguanylin Vascular endothelial growth factor (VEGF) Vasoactive intestinal peptide (VIP) Vasopressin (ADH) Xanthine Xanthosine α-keto-δ-Guanidinovaleric Acid α-N-Acetylarginine α1-Acid glycoprotein β-2-Microglobulin β-Endorphin β-Guanidinopropionic Acid β-Lipotropin γ-guanidinobutyric Acid λ-Ig Light Chain Base data Name S-Adenosylhomocysteine Molecular weight 384 Group Amino acid Class Water-soluble Added 14.01.2011 Reference Pubmed: 8514862 Submitted by Perna Reviewed by Abou Deif Normal concentrations (CN) Date Mean (+/-SD) (low Range - high Range) n Reference Submitted by Reviewed by Notes 18.06.2003 3.84 µg/L 1 Folate treatment and unbalanced methy... Perna Abou Deif [16] 08.01.2007 10.68 (+/-3.03) µg/L 1 S-adenosylhomocysteine hydrolase defi... Abou Deif Argiles [16] Grand mean 7.26 (+/-2.14) (3.84-10.68) µg/L 2 ANOVA Dispersion L:3.84, M:7.26, H:10.68 : A - (Minimal scatter: High consistency.) Uremic concentrations (CU) Date Mean (+/-SD) (low Range - high Range) n Reference Submitted by Reviewed by Notes 18.06.2003 230.40 (+/-38.40) µg/L 1 Folate treatment and unbalanced methy... Perna Abou Deif [16] Grand mean 230.40 (+/-38.40) µg/L 1 ANOVA Dispersion Relative increase (CU/CN) 31.74 times higher than the average normal concentration. Pathological associations Date Category Reference Comment 18.12.2001 Cardiovascular Plasma S-adenosylhomocysteine is a mo... Plasma S-Adenosylhomocysteine is a more sensitive marker of clinical cardiovascular disease than Homocysteine. Notes 16 Excluded from analysis of variance for missing arithmetic mean, standard deviation or sample count.