Uremic Solutes Database
Solute Details for S-Adenosylhomocysteine
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Base data
Name S-Adenosylhomocysteine
Molecular weight 384
Group Amino acid
Class Water-soluble
Added 14.01.2011
Reference Pubmed: 8514862
Submitted by Perna
Reviewed by Abou Deif

Normal concentrations (CN)
DateMean (+/-SD) (low Range - high Range)nReferenceSubmitted byReviewed byNotes
18.06.20033.84 µg/L1Folate treatment and unbalanced methy...PernaAbou Deif[16]
08.01.200710.68 (+/-3.03) µg/L1S-adenosylhomocysteine hydrolase defi...Abou DeifArgiles[16]
Grand mean7.26 (+/-2.14) (3.84-10.68) µg/L2
ANOVA
DispersionL:3.84, M:7.26, H:10.68 : A - (Minimal scatter: High consistency.)

Uremic concentrations (CU)
DateMean (+/-SD) (low Range - high Range)nReferenceSubmitted byReviewed byNotes
18.06.2003230.40 (+/-38.40) µg/L1Folate treatment and unbalanced methy...PernaAbou Deif[16]
Grand mean230.40 (+/-38.40) µg/L1
ANOVA
Dispersion

Relative increase (CU/CN) 31.74 times higher than the average normal concentration.

Pathological associations
DateCategoryReferenceComment
18.12.2001CardiovascularPlasma S-adenosylhomocysteine is a mo...Plasma S-Adenosylhomocysteine is a more sensitive marker of clinical cardiovascular disease than Homocysteine.

Notes
16Excluded from analysis of variance for missing arithmetic mean, standard deviation or sample count.