Uremic Solutes Database
Solute Details for Guanylin
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Base data
Name Guanylin
Molecular weight 1516
Group Peptide
Class Middle molecule
Added 16.09.2009
Reference Pubmed: 17651115
Submitted by Schepers
Reviewed by Abou Deif

Normal concentrations (CN)
DateMean (+/-SD) (low Range - high Range)nReferenceSubmitted byReviewed byNotes
25.09.19960.05 (+/-0.03) µg/L30Tissue distribution and plasma concen...Abou DeifArgiles[2] [15]
14.04.19970.05 (+/-0.01) µg/L32Increased plasma guanylin levels in p...Abou DeifArgiles[2]
Grand mean0.05 (+/-0.02) (0.05-0.05) µg/L62
ANOVAF(1,60) = 0.17, p=0.69: No significant differences between group means.
DispersionL:0.05, M:0.05, H:0.05 : A - (Minimal scatter: High consistency.)

Uremic concentrations (CU)
DateMean (+/-SD) (low Range - high Range)nReferenceSubmitted byReviewed byNotes
25.09.19966.16 (+/-2.70) µg/L9Tissue distribution and plasma concen...Abou DeifArgiles
14.04.199713.30 (+/-5.90) µg/L16Increased plasma guanylin levels in p...Abou DeifArgiles[2]
Grand mean10.73 (+/-4.99) (6.16-13.30) µg/L25
ANOVAF(1,23) = 74.12, p=0.00: Significant differences between group means.
DispersionL:6.16, M:10.73, H:13.30 : A - (Minimal scatter: High consistency.)

Relative increase (CU/CN) 225.66 times higher than the average normal concentration.

Pathological associations
No clinical associations available.

Notes
2Units reported as mol/l transformed to g/l as C(g/l) = [C(mol/l) * molecular weight]
15Standard error converted to standard deviation as SD = SEM * sqrt(n)