| Uremic Solutes Database |
| Solute Details for Guanylin |
| Switch to solute: |
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| Base data |
| Name |
Guanylin |
| Molecular weight |
1516 |
| Group |
Peptide |
| Class |
Middle molecule |
| Added |
16.09.2009 |
| Reference |
Pubmed: 17651115 |
| Submitted by |
Schepers |
| Reviewed by |
Abou Deif |
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| Normal concentrations (CN) |
| Date | Mean (+/-SD) (low Range - high Range) | n | Reference | Submitted by | Reviewed by | Notes | | 25.09.1996 | 0.05 (+/-0.03) µg/L | 30 | Tissue distribution and plasma concen... | Abou Deif | Argiles | [2] [15] | | 14.04.1997 | 0.05 (+/-0.01) µg/L | 32 | Increased plasma guanylin levels in p... | Abou Deif | Argiles | [2] | | Grand mean | 0.05 (+/-0.02) (0.05-0.05) µg/L | 62 | | | | ANOVA | F(1,60) = 0.17, p=0.69: No significant differences between group means. | | | | Dispersion | L:0.05, M:0.05, H:0.05 : A - (Minimal scatter: High consistency.) |
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| Uremic concentrations (CU) |
| Date | Mean (+/-SD) (low Range - high Range) | n | Reference | Submitted by | Reviewed by | Notes | | 25.09.1996 | 6.16 (+/-2.70) µg/L | 9 | Tissue distribution and plasma concen... | Abou Deif | Argiles | | | 14.04.1997 | 13.30 (+/-5.90) µg/L | 16 | Increased plasma guanylin levels in p... | Abou Deif | Argiles | [2] | | Grand mean | 10.73 (+/-4.99) (6.16-13.30) µg/L | 25 | | | | ANOVA | F(1,23) = 74.12, p=0.00: Significant differences between group means. | | | | Dispersion | L:6.16, M:10.73, H:13.30 : A - (Minimal scatter: High consistency.) |
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| Relative increase (CU/CN) |
225.66 times higher than the average normal concentration. |
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| Pathological associations |
| No clinical associations available. |
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| Notes |
| 2 | Units reported as mol/l transformed to g/l as C(g/l) = [C(mol/l) * molecular weight] | | 15 | Standard error converted to standard deviation as SD = SEM * sqrt(n) |
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