Solute Details for Monomethylamine - Uremic Solutes Database

Uremic Solutes Database

Solute Details for Monomethylamine

Switch to solute:

Base data

Name

Monomethylamine

Molecular weight

Group

Amine

Class

Water-soluble

Added

01.08.2012

Reference

Submitted by

Duranton

Reviewed by

Abou Deif

Normal concentrations (CN)

Date	Mean (+/-SD) (low Range - high Range)	n	Reference	Submitted by	Reviewed by	Notes
06.06.2010	30.90 (+/-6.10) µg/L	10	Relationship of impaired olfactory fu...	Abou Deif	Argiles
09.01.2011	320.00 (+/-40.00) mg/L	7	Colonic contribution to uremic solutes.	Abou Deif	Argiles
Grand mean	149.94 (+/-26.09) (30.90-320.00) µg/L	17
ANOVA	F(1,15) = 6347.22, p=0.00: Significant differences between group means.
Dispersion	L:30.90, M:149.94, H:320.00 : C - (Wide scatter: High uncertainty.)

Uremic concentrations (CU)

Date	Mean (+/-SD) (low Range - high Range)	n	Reference	Submitted by	Reviewed by	Notes
06.06.2010	84.20 (+/-20.80) µg/L	31	Relationship of impaired olfactory fu...	Abou Deif	Argiles
09.01.2011	580.00 (+/-100.00) µg/L	9	Colonic contribution to uremic solutes.	Abou Deif	Argiles
Grand mean	195.76 (+/-50.85) (84.20-580.00) µg/L	40
ANOVA	F(1,38) = 1129.47, p=0.00: Significant differences between group means.
Dispersion	L:84.20, M:195.76, H:580.00 : B - (Medium scatter: Considerable degree of uncertainty.)

Relative increase (CU/CN)

1.31 times higher than the average normal concentration.

Pathological associations

Date	Category	Reference	Comment
10.02.2001	Neurologic and CNS	Methylamine in human urine.	Methylamine is thought to play a significant part in central nervous system disturbances observed during renal and hepatic disease.
05.12.2005	Nephrologic	Methylamine, but not ammonia, is hypo...	Monomethylamine induces central hypophagic effects.

Notes

No notes.