Uremic Solutes Database
Solute Details for Monomethylamine
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Base data
Name Monomethylamine
Molecular weight 31
Group Amine
Class Water-soluble
Added 01.08.2012
Reference Pubmed: 22626821
Submitted by Duranton
Reviewed by Abou Deif

Normal concentrations (CN)
DateMean (+/-SD) (low Range - high Range)nReferenceSubmitted byReviewed byNotes
06.06.201030.90 (+/-6.10) µg/L10Relationship of impaired olfactory fu...Abou DeifArgiles
09.01.2011320.00 (+/-40.00) mg/L7Colonic contribution to uremic solutes.Abou DeifArgiles
Grand mean149.94 (+/-26.09) (30.90-320.00) µg/L17
ANOVAF(1,15) = 6347.22, p=0.00: Significant differences between group means.
DispersionL:30.90, M:149.94, H:320.00 : C - (Wide scatter: High uncertainty.)

Uremic concentrations (CU)
DateMean (+/-SD) (low Range - high Range)nReferenceSubmitted byReviewed byNotes
06.06.201084.20 (+/-20.80) µg/L31Relationship of impaired olfactory fu...Abou DeifArgiles
09.01.2011580.00 (+/-100.00) µg/L9Colonic contribution to uremic solutes.Abou DeifArgiles
Grand mean195.76 (+/-50.85) (84.20-580.00) µg/L40
ANOVAF(1,38) = 1129.47, p=0.00: Significant differences between group means.
DispersionL:84.20, M:195.76, H:580.00 : B - (Medium scatter: Considerable degree of uncertainty.)

Relative increase (CU/CN) 1.31 times higher than the average normal concentration.

Pathological associations
DateCategoryReferenceComment
10.02.2001Neurologic and CNSMethylamine in human urine.Methylamine is thought to play a significant part in central nervous system disturbances observed during renal and hepatic disease.
05.12.2005NephrologicMethylamine, but not ammonia, is hypo...Monomethylamine induces central hypophagic effects.

Notes
No notes.