| Uremic Solutes Database |
| Solute Details for Dihydroxyphenylalanine (PB-DOPA) |
| Switch to solute: |
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| Base data |
| Name |
Dihydroxyphenylalanine (PB-DOPA) |
| Molecular weight |
197 |
| Group |
Catecholamine |
| Class |
Protein-bound [4] |
| Added |
01.08.2012 |
| Reference |
Pubmed: 22626821 |
| Submitted by |
Duranton |
| Reviewed by |
Abou Deif |
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| Normal concentrations (CN) |
| Date | Mean (+/-SD) (low Range - high Range) | n | Reference | Submitted by | Reviewed by | Notes | | 12.12.2003 | 6.60 (+/-0.73) mg/L | 21 | Serum protein-bound 3,4-dihydroxyphen... | Abou Deif | Argiles | [2] | | Grand mean | 6.60 (+/-0.73) mg/L | 21 | | | | ANOVA | | | | | Dispersion | |
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| Uremic concentrations (CU) |
| Date | Mean (+/-SD) (low Range - high Range) | n | Reference | Submitted by | Reviewed by | Notes | | 12.12.2003 | 11.37 (+/-3.17) mg/L | 19 | Serum protein-bound 3,4-dihydroxyphen... | Abou Deif | Argiles | [2] | | Grand mean | 11.37 (+/-3.17) mg/L | 19 | | | | ANOVA | | | | | Dispersion | |
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| Relative increase (CU/CN) |
1.72 times higher than the average normal concentration. |
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| Pathological associations |
| Date | Category | Reference | Comment | | 14.12.2000 | Biochemical | Metabolism of protein-bound DOPA in m... | Protein-bound DOPA (PB-DOPA) has the capacity to inflict secondary damage on important biomolecules such as DNA. |
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| Notes |
| 2 | Units reported as mol/l transformed to g/l as C(g/l) = [C(mol/l) * molecular weight] | | 4 | This protein-bound solute has a molecular weight conforming to middle molecules. |
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