Uremic Solutes Database |
Solute Details for Dihydroxyphenylalanine (PB-DOPA) |
Switch to solute: |
|
|
Base data |
Name |
Dihydroxyphenylalanine (PB-DOPA) |
Molecular weight |
197 |
Group |
Catecholamine |
Class |
Protein-bound [4] |
Added |
01.08.2012 |
Reference |
Pubmed: 22626821 |
Submitted by |
Duranton |
Reviewed by |
Abou Deif |
|
Normal concentrations (CN) |
Date | Mean (+/-SD) (low Range - high Range) | n | Reference | Submitted by | Reviewed by | Notes | 12.12.2003 | 6.60 (+/-0.73) mg/L | 21 | Serum protein-bound 3,4-dihydroxyphen... | Abou Deif | Argiles | [2] | Grand mean | 6.60 (+/-0.73) mg/L | 21 | | | ANOVA | | | | Dispersion | |
|
|
Uremic concentrations (CU) |
Date | Mean (+/-SD) (low Range - high Range) | n | Reference | Submitted by | Reviewed by | Notes | 12.12.2003 | 11.37 (+/-3.17) mg/L | 19 | Serum protein-bound 3,4-dihydroxyphen... | Abou Deif | Argiles | [2] | Grand mean | 11.37 (+/-3.17) mg/L | 19 | | | ANOVA | | | | Dispersion | |
|
|
Relative increase (CU/CN) |
1.72 times higher than the average normal concentration. |
|
Pathological associations |
Date | Category | Reference | Comment | 14.12.2000 | Biochemical | Metabolism of protein-bound DOPA in m... | Protein-bound DOPA (PB-DOPA) has the capacity to inflict secondary damage on important biomolecules such as DNA. |
|
|
Notes |
2 | Units reported as mol/l transformed to g/l as C(g/l) = [C(mol/l) * molecular weight] | 4 | This protein-bound solute has a molecular weight conforming to middle molecules. |
|
|
|