Uremic Solutes Database HOME   SOLUTE LIST   SOLUTE DETAILS   STATISTICS   LOGIN   REGISTER Solute Details for p-Cresylsulfate (total) Switch to solute: 1-Methyladenosine 1-Methylguanosine 1-Methylinosine 2-Heptenal 2-Hexenal 2-Nonenal 2-Octenal 3-Carboxy-4-Methyl-5-Propyl-2-Furanpropanoic Acid (CMPF) 3-Deoxyglucosone 4-Decenal 4-HO-Decenal 4-HO-Hexenal 4-HO-Nonenal 4-HO-Octenal 4-Pyridone-3-carboxamide-1-β-D-ribonucleoside 8-Hydroxy-2’-deoxyguanosine Adiponectin Adrenomedullin Angiogenin Arab(in)itol Argininic Acid Asymetric Dimethylarginine (ADMA) Atrial Natriuretic Peptide (ANP) Basic fibroblast growth factor (BFGF) Calcitonin gene-related peptide (CGRP) Cholecystokinin Clara cell protein (CC16) Complement Factor D Creatine Creatinine Cystatin C Cytidine Decanal Degranulation Inhibiting Protein I Delta-sleep Inducing Peptide Dihydroxyphenylalanine (PB-DOPA) Dimethylamine Dimethylglycine Endothelin Erythritol Ethylamine Fructoselysine Glyoxal Guanidine Guanidinosuccinic acid Guanylin Heptanal Hexanal Hippuric acid (total) Homocysteine Hyaluronic acid (Hyaluronan) Hypoxanthine Indican Indole-3-acetic acid (free) Indole-3-acetic acid (total) Indoxyl sulfate (free) Indoxyl sulfate (total) Indoxyl-β-D-glucoronide Inosine Insulin-like growth factor 1 (IGF-1) Interleukin-10 Interleukin-18 Interleukin-1β Interleukin-6 Kinurenine Kynurenic Acid Leptin Malondialdehyde (MDA) Mannitol Melatonin Methionine-Enkephalin Methylglyoxal Methylguanidine Monomethylamine Motiline Myoinositol N(6)-Carboxymethyllysine (CML) N-methyl-2-pyridone-5-carboxamide N-methyl-4-pyridone-3-carboxamide N2,N2-Dimethylguanosine N4-Acetylcytidine N6-Methyladenosine N6-Threonylcarbamoyladenosine Neopterin Neuropeptide Y Nicotinamide Nonanal Orotic Acid Orotidine Osteocalcin Oxalate p-Cresylsulfate (free) p-Cresylsulfate (total) Parathyroid hormone Pentosidine Phenol Phenylacetic acid Phenylacetylglutamine Pseudouridine Putrescine Quinolinic Acid Resistin Retinol Binding Protein (RBP) S-Adenosylhomocysteine Sorbitol Substance P Symetric Dimethylarginine (SDMA) Taurocyamine Threitol Trimethylamine Trimethylamine-N-oxide Tumor Necrosis Factor Alpha (TNF) Urea Uric Acid Uridine Uroguanylin Vascular endothelial growth factor (VEGF) Vasoactive intestinal peptide (VIP) Vasopressin (ADH) Xanthine Xanthosine α-keto-δ-Guanidinovaleric Acid α-N-Acetylarginine α1-Acid glycoprotein β-2-Microglobulin β-Endorphin β-Guanidinopropionic Acid β-Lipotropin γ-guanidinobutyric Acid λ-Ig Light Chain Base data Name p-Cresylsulfate (total) Molecular weight 187 Group Phenol Class Protein-bound [4] Added 01.08.2012 Reference Pubmed: 22626821 Submitted by Beige Reviewed by Abou Deif Normal concentrations (CN) Date Mean (+/-SD) (low Range - high Range) n Reference Submitted by Reviewed by Notes 06.06.2010 3.80 (+/-3.30) mg/L 4 Relationship of impaired olfactory fu... Abou Deif Argiles 09.01.2011 1.90 (+/-1.30) mg/L 6 Colonic contribution to uremic solutes. Abou Deif Argiles 08.03.2011 1.50 (+/-2.30) mg/L 21 Levels of circulating endothelial pro... Abou Deif Argiles Grand mean 1.87 (+/-2.31) (1.50-3.80) mg/L 31 ANOVA F(2,28) = 1.80, p=0.18: No significant differences between group means. Dispersion L:1.50, M:1.87, H:3.80 : A - (Minimal scatter: High consistency.) Uremic concentrations (CU) Date Mean (+/-SD) (low Range - high Range) n Reference Submitted by Reviewed by Notes 06.06.2010 37.70 (+/-18.70) mg/L 31 Relationship of impaired olfactory fu... Abou Deif Argiles 12.11.2010 19.60 (+/-17.80) mg/L 8 Protein-bound uraemic toxin removal i... Abou Deif Argiles 08.03.2011 26.70 (+/-13.30) mg/L 38 Levels of circulating endothelial pro... Abou Deif Argiles 03.05.2012 18.90 (+/-17.30) mg/L 139 Free p-cresylsulphate is a predictor ... Abou Deif Argiles Grand mean 23.00 (+/-16.90) (18.90-37.70) mg/L 216 ANOVA F(3,212) = 11.58, p=0.00: Significant differences between group means. Dispersion L:18.90, M:23.00, H:37.70 : A - (Minimal scatter: High consistency.) Relative increase (CU/CN) 12.27 times higher than the average normal concentration. Pathological associations Date Category Reference Comment 09.07.2007 Cardiovascular P-cresylsulphate, the main in vivo me... P-cresylsulfate has a pro-inflammatory effect on unstimulated leucocytes. This could contribute to the propensity to vascular disease in the uraemic population. 02.11.2012 Nephrologic p-Cresyl sulphate and indoxyl sulphat... P-Cresyl-Sulfate levels may help in predicting the risk of renal progression in patients having different stages of CKD. Notes 4 This protein-bound solute has a molecular weight conforming to middle molecules.